1887

Abstract

SUMMARY

The technique of virus RNA-cellular DNA hybridization in solution with DNA excess was used to compare the nucleotide sequences of the 70S RNA genome of the Kirsten mouse sarcoma virus (Ki-MSV) with that of mouse erythroblastosis virus (MEV) which gave rise to Ki-MSV after propagation in rat. It is suggested that a loss of about 30% of the genomic sequences of MEV with a concomitant gain of roughly equal amounts of rat-specific sequences in a genetically stable recombinant state led to the formation of Ki-MSV.

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1975-08-01
2022-09-25
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