1887

Abstract

Summary

Sixty mutants were isolated from the Pacheco strain of type O foot-and-mouth disease virus after treatment with either 5-fluorouracil or hydroxylamine. The conditions affecting recombination and assay of the recombinants were standardized. Using two mutants resistant to guanidine, three-factor crosses, supported by two-factor crosses, located 34 of the mutations in a linear arrangement. The recombination frequencies between certain pairs of mutations were additive. The guanidine character of the two resistant mutants mapped as a single site mutation and was located near the middle of the map.

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/content/journal/jgv/10.1099/0022-1317-27-3-355
1975-06-01
2019-10-22
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-27-3-355
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