1887

Abstract

Summary

After an initial acute infection with cell killing, chicken or duck embryo fibroblasts infected in culture with reticuloendotheliosis viruses set up a chronic infection with no cell killing or morphological transformation. Essentially all of the chronically infected cells produced virus. The virus production was not sensitive to cytosine arabinoside or mitomycin C as was virus production in an acute infection.

The chronically infected cells had a strong group-specific resistance to the c.p.e. of superinfecting reticuloendotheliosis viruses. However, they were sensitive to vesicular stomatitis virus and avian leukosis-sarcoma viruses.

After double infection, single cells produced reticuloendotheliosis virus and avian leukosis-sarcoma virus.

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/content/journal/jgv/10.1099/0022-1317-27-3-267
1975-06-01
2019-11-12
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-27-3-267
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