The Influence of Emetine on the Induction of Interferon by Poly-I:Poly-C in Swiss Mice

H. Schellekens; J. H. P. M. Huffmeyer; L. J. L. D. Van Griensven

doi:10.1099/0022-1317-26-2-197

The Influence of Emetine on the Induction of Interferon by Poly-I:Poly-C in Swiss Mice

H. Schellekens, J. H. P. M. Huffmeyer and L. J. L. D. Van Griensven
First Published: 01 February 1975 https://doi.org/10.1099/0022-1317-26-2-197

Abstract

Summary

The effect of emetine on the in vivo production of interferon by Swiss mice stimulated with poly-I:poly-C, was studied. 100 µg of emetine per mouse yielded a 16-fold increase in interferon production. Maximal production of interferon was achieved 2 h after the simultaneous injection of emetine and poly-I:poly-C.

Received: 10/07/1974
Accepted: 08/10/1974
Published Online: 01/02/1975

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Journal of General Virology

Volume 26, Issue 2

Research Article

Free

The Influence of Emetine on the Induction of Interferon by Poly-I:Poly-C in Swiss Mice

Abstract

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Most cited this month Most Cited RSS feed

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