1887

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Volume 26, Issue 1

Transformation of Hamster Embryo Cells by Bovine Adenovirus Type 3 (Strain WBR-1) Free

Abstract

SUMMARY

Bovine adenovirus type 3 (BAV-3), strain WBR-1, quantitatively transforms hamster embryo carcass cells with a maximum efficiency of 4.7 × 10 p.f.u./focus-forming units (f.f.u.). This frequency is significantly inhibited by the presence of 1.8 m of Ca. The transformed cells are highly tumourigenic in hamsters and possess T- and tumour-specific transplantation antigens. BAV-3 is one of the most oncogenic of the adenoviruses and an ideal model virus for the study of transformation.

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© Society for General Microbiology, 1975
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/content/journal/jgv/10.1099/0022-1317-26-1-141
1975-01-01
2024-04-25
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References

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In vitro Transformation of Hamster Embryo Cells by Bovine Adenovirus Type 3 (Strain WBR-1)
J. Gen. Virol. 26, 141 (1975); https://doi.org/10.1099/0022-1317-26-1-141
/content/journal/jgv/10.1099/0022-1317-26-1-141
/content/journal/jgv/10.1099/0022-1317-26-1-141
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