1887

Abstract

SUMMARY

Newly formed gs-1 antigen of RD-114 virus was detected by the indirect fluorescent antibody (IFA) procedure in the cytoplasm of the D-17 dog cell line at 24 h post-infection in approx. 30% of the cells. Virus-induced membrane antigen was present in approx. 50% of the cells by 48 h, at which time new infectious virus was being produced. Polykaryons were observed in infected cells. Their formation paralleled production of virus, as determined by the IFA membrane staining technique.

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1974-10-01
2024-04-25
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References

  1. Avrameas S., Ternynck T. 1969; The cross-linking of proteins with glutaraldehyde and its use for the preparation of immunoadsorbents. Immunochemistry 6:53–66
    [Google Scholar]
  2. Boone C. W., Church E. C., Mcallister R. M. 1973; Testing by the “paired-label” antibody technique for feline leukemia virus-induced cell surface antigens (FeLV-CSA) on the surface of human rhabdomyosarcoma cells releasing RD-114 virus. Virology 55:157–162
    [Google Scholar]
  3. Chuat J. C., Lasquellec F., L’hirondel A. M., Boiron M. 1971; Studies on murine sarcoma virus. II. Detection of group-specific antigens by immunofluorescence. International Journal of Cancer 7:101–111
    [Google Scholar]
  4. Clarke J. K., Samuels J., Dermott E., Gay F. W. 1970; Carrier cultures of simian foamy virus. Journal of Virology 5:624–631
    [Google Scholar]
  5. Gregoriades A., Old L. J. 1969; Isolation and some characteristics of a group-specific antigen of the murine leukemia viruses. Virology 37:189–202
    [Google Scholar]
  6. Hampar B., Gilden R. V., Kelloff G., Oroszlan S., Simms D. 1971; Immunofluorescent detection of murine and hamster C-type virus species-specific (gs-1) determinants by monospecific guinea-pig sera and interspecies-specific (gs-3) determinants by tumor bearing rat sera. International Journal of Cancer 8:425–431
    [Google Scholar]
  7. Hampar B., Rand K. H., Lerner R. A., Del Villano B. C. Jun, Mcallister R. M., Martos L. M., Derge J. G., Long C. W., Gilden R. N. 1973; Formation of syncytia in human lymphoblastoid cells infected with type C viruses. Virology 55:453–463
    [Google Scholar]
  8. Huebner R. J., Armstrong D., Okuyan M., Sarma P. S., Turner H. C. 1964; Specific Complement fixing viral antigens in hamster and guinea pig tumors induced by the Schmidt-Ruppin strain of avian sarcoma. Proceedings of the National Academy of Sciences of the United States of America 51:742–749
    [Google Scholar]
  9. Kelloff G., Vogt P. K. 1966; Localization of avian tumor virus group-specific antigen in cell and virus. Virology 29:377–384
    [Google Scholar]
  10. Klement V., Mcallister R. M. 1972; Syncytial cytopathic effect in KB cells of a C-type RNA virus isolated from human rhabdomyosarcoma. Virology 50:305–308
    [Google Scholar]
  11. Lejneva O. M., Abelev G. I. 1970; Immunofluorescent study of the group-specific antigen of murine leukemia viruses. International Journal of Cancer 6:153–159
    [Google Scholar]
  12. Lennette E. H. 1969; General Principles Underlying Laboratory Diagnosis of Viral and Rickettsial Infections. In Diagnostic Procedures for Viral and Rickettsial Infections 4th edition chapter 11–65 Edited by Lennette E. H., Schmidt N. J. New York: The American Public Health Association, Inc;
    [Google Scholar]
  13. Livingston D. M., Todaro G. J. 1973; Endogenous type-C virus from a cat cell clone with properties distinct from previously described feline type-C viruses. Virology 53:142–151
    [Google Scholar]
  14. Mcallister R. M., Nicolson M., Gardner M. B., Rongey R. W., Rasheed S., Sarma P. S., Huebner R. J., Hatanaka M., Oroszlan S., Gilden R. V., Kabigting A., Vernon L. 1972; C-type virus released from cultured human rhabdomyosarcoma cells. Nature New Biology 235:3–6
    [Google Scholar]
  15. Oroszlan S., Bova D., White M. H. M., Toni R., Foreman C., Gilden R. V. 1972; Purification and immunological characterization of the major internal protein of the RD114 virus. Proceedings of the National Academy of Sciences of the United States of America 69:1211–1215
    [Google Scholar]
  16. Oroszlan S., Fisher C. L., Stanley T. B., Gilden R. V. 1970; Proteins of the murine C-type RNA tumour viruses: isolation of a group-specific antigen by isoelectric focusing. Journal of General Virology 8:1–10
    [Google Scholar]
  17. Payne F. E., Solomon J. J., Purchase H. G. 1966; Immunofluorescent studies of group-specific antigen of the avian sarcoma-leukosis viruses. Proceedings of the National Academy of Sciences of the United States of America 55:341–349
    [Google Scholar]
  18. Rand K. H., Long C. 1972; Syncytial assay for the putative human C-type virus, RD-114, utilizing human cells transformed by Rouse sarcoma virus. Nature New Biology 240:187–190
    [Google Scholar]
  19. Riggs J. L. 1971; An immunofluorescent test for feline leukemia and sarcoma virus antigens and antibodies. Journal of the American Veterinary Medical Association 158:1085–1087
    [Google Scholar]
  20. Ubertini T., Noronha F., Post J. E., Rickard C. G. 1971; A fluorescent antibody technique for the detection of the group-specific antigen of feline leukemia virus in infected tissue-culture cells. Virology 44:219–222
    [Google Scholar]
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