1887

Abstract

SUMMARY

Experiments were conducted to study the photodynamic inactivation of blue-green virus N-1 (cyanophage N-1) sensitized with acridine orange. Acridine orange at concentrations of 1 to 5 µg/ml displayed a dose related protection of free virus, when irradiated at 268 nm. The same concentrations of acridine orange produced inactivation of virus, as a logarithmic response to dye concentration, when irradiated at 490 nm.

The resistance of cyanophage N-1 to osmotic shock is in accord with the rapid acridine orange sensitization of virus in darkness, and the interpretation that the protein coat of N-1, like that of the T-odd coliphages, in highly permeable.

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1974-10-01
2021-10-20
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