1887

Abstract

Summary

Single-stranded polynucleotides (poly I and poly C), which do not generally have antiviral activity, became effective inducers of interferon when aggregated with different polycations. Poly I was consistently more active than poly C. The biological activity of the complexes depended more on the nature of the polycationic component than on the presence of the complementary base residue: introduction of covalently bound cytosine residue into the poly I—polybase complex did not have any significant effect.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-24-2-385
1974-08-01
2019-11-17
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-24-2-385
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error