Abortive Infection and Transformation of Human Embryonic Fibroblasts by Virus Free

Abstract

SUMMARY

Abortive transformation of human embryonic fibroblasts was induced by virus. The parameters studied in order to test the establishment of a persistent infection and transformation of cells were: (1) virus interference and interferon production; (2) alterations of cell morphology and growth; (3) presence of neoantigens; (4) karyotype. The possible mechanisms leading to an abortive transformation are discussed.

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1974-08-01
2024-03-29
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