%0 Journal Article %A Barbanti-Brodano, G. %A Mannini-Palenzona, A. %A Varoli, O. %A Portolani, M. %A La Placa, M. %T Abortive Infection and Transformation of Human Embryonic Fibroblasts by Molluscum contagiosum Virus %D 1974 %J Journal of General Virology, %V 24 %N 2 %P 237-246 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-24-2-237 %I Microbiology Society, %X SUMMARY Abortive transformation of human embryonic fibroblasts was induced by Molluscum contagiosum virus. The parameters studied in order to test the establishment of a persistent infection and transformation of cells were: (1) virus interference and interferon production; (2) alterations of cell morphology and growth; (3) presence of neoantigens; (4) karyotype. The possible mechanisms leading to an abortive transformation are discussed. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-24-2-237