1887

Abstract

SUMMARY

A group of bacteriophages active on have been isolated from a number of animal sera including calf, foetal calf, lamb, chicken and rabbit. The phages are specific for ; no lytic activity was detected on 36 strains of , 6 strains of and seven strains of the genus . Some characteristics of these bacteriophages such as adsorption constants and single-step growth experiments as well as electron micrographs are presented. The host-phage system readily develops a stable phage-bacterium association, i.e. phage carrier cultures. Broth cultures infected with phage at high multiplicities, demonstrated active bacterial growth coincident with phage production. Cultivation of phage carrier strain 12 in medium containing phage antisera eliminated phage carriage. The phage-cured cultures yielded a mixture of phage-sensitive and phage-resistant clones and evidence was obtained of a rapid rate of alternation between these two phenotypes. The simultaneous production of both phage and bacteria in carrier cultures may be ascribed to the continuous development of phage-sensitive organisms from a phage-resistant population.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-24-1-179
1974-07-01
2024-03-29
Loading full text...

Full text loading...

/deliver/fulltext/jgv/24/1/JV0240010179.html?itemId=/content/journal/jgv/10.1099/0022-1317-24-1-179&mimeType=html&fmt=ahah

References

  1. Adams M. H. 1959 In Bacteriophages New York: Interscience Publishers, Inc;
    [Google Scholar]
  2. Baess L. 1971; Report on a pseudolysogenic mycobacterium and a review of the literature concerning pseudolysogeny. Acta pathologica et microbiologica scandinavica (Section B) 79:428–434
    [Google Scholar]
  3. Bradley D. E. 1967; Ultrastructure of bacteriophages and bacteriocins. Bacteriological Reviews 31:230–314
    [Google Scholar]
  4. Finegold S. M., Sutter V. L., Cato E. P., Holdeman L. V. 1970 In Rapid Diagnostic Methods in Medical Microbiology48–66 Edited by Graber C. D. Baltimore: Williams & Wilkins;
    [Google Scholar]
  5. Keller R. 1973; Isolation of bacteroides bacteriophages. Abstracts of Annual Meeting of the American Society for Microbiology (Miami) pp 228
    [Google Scholar]
  6. Keller R., Engley F. B. Jun 1958; Fate of bacteriophage particles introduced into mice by various routes. Proceedings of the Society for Experimental Biology and Medicine 98:577–580
    [Google Scholar]
  7. Keller R., Zatzman M. L. 1959; Studies on the factors concerned in the disappearance of bacteriophage particles from the animal body. Journal of Immunology 83:167–172
    [Google Scholar]
  8. Li K., Barksdale L., Garmise L. 1961; Phenotypic alterations associated with the bacteriophage carrier state of Shigella dysenteriae . Journal of General Microbiology 24:355–367
    [Google Scholar]
  9. Lieb M. 1970; A mutants which persist as plasmids. Journal of Virology 6:218–225
    [Google Scholar]
  10. Lwoff A. 1953; Lysogeny. Bacteriological Reviews 17:269–337
    [Google Scholar]
  11. Merrill C. R., Friedman T. B., Attallah A. F. M., Grier M. R., Krell K., Yarkin R. 1972; Isolation of bacteriophages from commercial sera. In vitro 8:91–93
    [Google Scholar]
  12. Nacescu N., Brandis H., Werner H. 1972; Isolierung von zwei Bacteroides fragilis-Phagen aus Abwasser und Nachweis Lysoginer B. fragilis-Stamme. Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene 219:522–529
    [Google Scholar]
  13. Sabiston C. B. Jun, Cohl M. E. 1969; Bacteriophage virulent in species of the genus Bacteroides. Journal of Dental Research48–599
    [Google Scholar]
  14. Signer E. R. 1989; Plasmid formation: a new mode of lysogeny by phage A. Nature, London 223158–160
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-24-1-179
Loading
/content/journal/jgv/10.1099/0022-1317-24-1-179
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error