1887

Abstract

SUMMARY

Hybrids from poly dI and poly r(5-halogenocytidylic acids) having ’s in the region of 60 °C are inactive as interferon inducers thus confirming the requirement for a free 2′-hydroxyl group in both the poly I and poly C strands of poly rI.poly rC.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-23-3-331
1974-06-01
2022-01-21
Loading full text...

Full text loading...

/deliver/fulltext/jgv/23/3/JV0230030331.html?itemId=/content/journal/jgv/10.1099/0022-1317-23-3-331&mimeType=html&fmt=ahah

References

  1. Black D. R., Eckstein F., Hobbs J. B., Sternbach H., Merigan T. C. 1972; The antiviral activity of certain thiophosphate and 2′-chloro substituted polynucleotide homopolymer duplexes. Virology 48:537–545
    [Google Scholar]
  2. Bollum F. J. 1966; Preparation of deoxynucleotide polymerising enzymes from calfthymus gland. In Procedure in Nucleic Acid Researeh vol 1284–295 Edited by Cantoni E., Davies D. New York: Harper and Row;
    [Google Scholar]
  3. Chamberlain M. J., Patterson D. L. 1965; Physical and chemical characterisation of the ordered complexes formed between polyinosinic acid, polycytidylic acid and their deoxyribo-analogues. Journal of Molecular Biology 12:410–428
    [Google Scholar]
  4. Colby C. 1971; The induction of interferon by natural and synthetic polynucleotides. In Progress in Nucleic Acid Research and Molecular Biology vol 111–32 Edited by Davidson N. J., Cohn W. E. New York and London: Academic Press;
    [Google Scholar]
  5. Colby C., Chamberlin M. J. 1969; The specificity of interferon induction in chick embryo ceils by helical RNA. Proceedings of the National Academy of Sciences of the United States of America 63:160–167
    [Google Scholar]
  6. De Clercq E., Eckstein V., Merigan T. C. 1970; Structural requirements for synthetic polyanions to act as interferon inducers. Annals of the New York Academy of Sciences 173:444–461
    [Google Scholar]
  7. De Clercq E., Wells R. D., Merigan T. C. 1972; Studies of the antiviral activity and cell interaction of synthetic double stranded polyribo- and potydeoxyribonucleotides. Virology 47:405–415
    [Google Scholar]
  8. Eaton M. A. W., Hutchinson D. W. 1972; Poly(5-chlorocytidylic acid). Biochemistry 11:3162–3167
    [Google Scholar]
  9. Field A. R., Tytell A. A., Lampson G. P., Hilleman M. R. 1967; Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes. Proceedings of the National Academy of Sciences of the United States of America 58:1004–1010
    [Google Scholar]
  10. Finter N. B. 1969; Dye uptake methods for assessing viral cytopathogenicity and their application to interferon assays. Journal of General Virology 5:419–427
    [Google Scholar]
  11. Howard F. B., Frazier J., Miles H. T. 1969; Interaction of poly(5-bromocytidylic acid) with polyinosinic acid. Journal of Biological Chemistry1291–1302
    [Google Scholar]
  12. Michelson A. M., Monny C. 1967; Polynucleotide analogues. XII. Poly(5-bromocytidylic acid) and poly-(5-iodocytidylic acid). Biochimica et biophysica acta 149:88–98
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-23-3-331
Loading
/content/journal/jgv/10.1099/0022-1317-23-3-331
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error