1887

Abstract

SUMMARY

Virus-specific protein synthesis has been studied in unsynchronized and in starvation-synchronized infections of u.v.-irradiated host cells by X174 and a set of X conditional lethal mutants. Several virus-specific protein species were detected in association with the host cell membrane at various times during the virus reproduction cycle; virus-specific proteins were also detected in the host cell cytoplasm. The intracellular distribution, between the cell membrane fraction and the cell cytoplasm fraction, of virus proteins was measured under a variety of experimental conditions. The possible significance of the presence of virus proteins on the host cell membrane is discussed.

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/content/journal/jgv/10.1099/0022-1317-23-3-309
1974-06-01
2022-01-25
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