%0 Journal Article %A Kouri, G. %A Aguilera, A. %A Rodriguez, Pilar %A Korolev, M. %T A Study of Microfoci and Inclusion Bodies produced by Rubella Virus in the RK-13 Cell Line %D 1974 %J Journal of General Virology, %V 22 %N 1 %P 73-80 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-22-1-73 %I Microbiology Society, %X SUMMARY A study was made of the mechanism of microfocus formation and of the nature of the inclusion bodies that appear in the cytoplasm of RK-13 cells infected by rubella virus. Direct passage of virus particles from one cell to another, at least in the early stages of the infection, is posed as a possibility, and the lysosomal nature of the cytoplasmic inclusion bodies is demonstrated by histochemical methods. A description is given of conditions required in the monolayer for the formation of a microfocus, which is the characteristic manifestation of the c.p.e. of the rubella virus in this cellular system. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-22-1-73