The Significance of Influenza Virus Neuraminidase in Immunity Free

Abstract

SUMMARY

The neuraminidase of the Rostock strain of fowl plague virus (FPV) was found to be serologically closely related to the enzyme of swine influenza virus, whereas the haemagglutinins were distinct. When chickens were immunized with the apathogenic swine influenza virus, they were fully protected against an infection with the highly pathogenic FPV which killed non-immunized birds within 2 days. These experiments provide conclusive evidence that a protective capacity can also be attributed to the neuraminidase of influenza viruses.

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/content/journal/jgv/10.1099/0022-1317-22-1-35
1974-01-01
2024-03-29
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