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Mouse cells (MSV-IF +) are completely non-permissive to NDV; however, they produce interferon when NDV is used as an inducer. Eight h after infection these cells synthesize a virus ‘minus’ strand RNA which anneals to the extent of 57 to 97% with virus ‘plus’ strand RNA. This synthesis disappears gradually up to 48 h after infection, and is not modified by the incubation temperature (37 °C or 40 °C) of the infected cells.
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