The infection of MDBK cells by bovine syncytial virus did not result in the formation of syncytia. Plaques of infected cells were dispersed into single cells and quantitative studies were made on the conditions which influenced the spread of the virus. The stimulation of cell metabolism greatly enhanced the spread of virus, which was inhibited by bromodeoxyuridine.
MalmquistW. A.,
Van Der MaatenM.J.,
BootheA.D.1969; Isolation, immunodiffusion, immuno-fluorescence and electron microscopy of a syncitial virus of lymphosarcomatous and apparently normal cattle. Cancer Research 29:188