1887

Abstract

SUMMARY

Mouse peritoneal macrophages from C57 Bl and NIH mice were examined after infection with polyoma virus. Cell DNA synthesis was stimulated in both cell types to the same extent between two and three days after addition of virus. Morphological changes appearing soon after infection were reversed by the second or third day. The cells did not acquire other properties associated with the transformed state. Treatment with mouse interferon up to 48 h after infection inhibited the virus-induced host DNA synthesis while morphological changes were not affected.

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/content/journal/jgv/10.1099/0022-1317-21-2-391
1973-11-01
2021-10-16
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