Early Ultrastructural Changes Induced in BHK Cell Nuclei by Frog Virus 3. A Possible Mechanism for the Impairment of Cellular DNA Synthesis

Gabriella Campadelli-Fiume; M. Mercedes Bragaglia; F. Costanzo; Laura Foà; M. La Placa

doi:10.1099/0022-1317-21-1-197

Early Ultrastructural Changes Induced in BHK Cell Nuclei by Frog Virus 3. A Possible Mechanism for the Impairment of Cellular DNA Synthesis

Gabriella Campadelli-Fiume, M. Mercedes Bragaglia, F. Costanzo, Laura Foà and M. La Placa
First Published: 01 October 1973 https://doi.org/10.1099/0022-1317-21-1-197

Abstract

Summary

Evidence is presented that, in FV-3 infected BHK cell nuclei, the inhibition of RNA synthesis is paralleled by chromatin condensation. Inhibition of DNA synthesis could be due to the unavailability of the condensed chromatin to act as template.

Received: 26/03/1973
Accepted: 22/06/1973
Published Online: 01/10/1973

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-21-1-197

1973-10-01

2021-04-16

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-21-1-197

Most cited this month Most Cited RSS feed

- The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection
  
  Paul Kellam and Wendy Barclay
- Characteristics of the Microplate Method of Enzyme-Linked Immunosorbent Assay for the Detection of Plant Viruses
  
  M. F. Clark and A. N. Adams
- Updated classification of norovirus genogroups and genotypes
  
  Preeti Chhabra, Miranda de Graaf, Gabriel I. Parra, Martin Chi-Wai Chan, Kim Green, Vito Martella, Qiuhong Wang, Peter A. White, Kazuhiko Katayama, Harry Vennema, Marion P. G. Koopmans and Jan Vinjé
- ICTV Virus Taxonomy Profile: Geminiviridae
  
  F. Murilo Zerbini, Rob W Briddon, Ali Idris, Darren P Martin, Enrique Moriones, Jesús Navas-Castillo, Rafael Rivera-Bustamante, Philippe Roumagnac, Arvind Varsani and ICTV Report Consortium
- Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5
  
  F. L. Graham, J. Smiley, W. C. Russell and R. Nairn
- ICTV Virus Taxonomy Profile: Flaviviridae
  
  Peter Simmonds, Paul Becher, Jens Bukh, Ernest A. Gould, Gregor Meyers, Tom Monath, Scott Muerhoff, Alexander Pletnev, Rebecca Rico-Hesse, Donald B. Smith, Jack T. Stapleton and ICTV Report Consortium
- Mechanisms and enzymes involved in SARS coronavirus genome expression
  
  Volker Thiel, Konstantin A. Ivanov, Ákos Putics, Tobias Hertzig, Barbara Schelle, Sonja Bayer, Benedikt Weißbrich, Eric J. Snijder, Holger Rabenau, Hans Wilhelm Doerr, Alexander E. Gorbalenya and John Ziebuhr
- SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
  
  Natacha S. Ogando, Tim J. Dalebout, Jessika C. Zevenhoven-Dobbe, Ronald W.A.L. Limpens, Yvonne van der Meer, Leon Caly, Julian Druce, Jutte J. C. de Vries, Marjolein Kikkert, Montserrat Bárcena, Igor Sidorov and Eric J. Snijder
- Conservation of substrate specificities among coronavirus main proteases
  
  Annette Hegyi and John Ziebuhr
- Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment
  
  Susanna K. P. Lau, Candy C. Y. Lau, Kwok-Hung Chan, Clara P. Y. Li, Honglin Chen, Dong-Yan Jin, Jasper F. W. Chan, Patrick C. Y. Woo and Kwok-Yung Yuen
More Less

Journal of General Virology

Volume 21, Issue 1

Research Article

Free

Early Ultrastructural Changes Induced in BHK Cell Nuclei by Frog Virus 3. A Possible Mechanism for the Impairment of Cellular DNA Synthesis

Abstract

Most read this month

Most cited this month Most Cited RSS feed

The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection

Characteristics of the Microplate Method of Enzyme-Linked Immunosorbent Assay for the Detection of Plant Viruses

Updated classification of norovirus genogroups and genotypes

ICTV Virus Taxonomy Profile: Geminiviridae

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

ICTV Virus Taxonomy Profile: Flaviviridae

Mechanisms and enzymes involved in SARS coronavirus genome expression

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

Conservation of substrate specificities among coronavirus main proteases

Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment