Early Ultrastructural Changes Induced in BHK Cell Nuclei by Frog Virus 3. A Possible Mechanism for the Impairment of Cellular DNA Synthesis

Gabriella Campadelli-Fiume; M. Mercedes Bragaglia; F. Costanzo; Laura Foà; M. La Placa

doi:10.1099/0022-1317-21-1-197

Early Ultrastructural Changes Induced in BHK Cell Nuclei by Frog Virus 3. A Possible Mechanism for the Impairment of Cellular DNA Synthesis

Gabriella Campadelli-Fiume, M. Mercedes Bragaglia, F. Costanzo, Laura Foà and M. La Placa
First Published: 01 October 1973 https://doi.org/10.1099/0022-1317-21-1-197

Abstract

Summary

Evidence is presented that, in FV-3 infected BHK cell nuclei, the inhibition of RNA synthesis is paralleled by chromatin condensation. Inhibition of DNA synthesis could be due to the unavailability of the condensed chromatin to act as template.

Received: 26/03/1973
Accepted: 22/06/1973
Published Online: 01/10/1973

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Journal of General Virology

Volume 21, Issue 1

Research Article

Free

Early Ultrastructural Changes Induced in BHK Cell Nuclei by Frog Virus 3. A Possible Mechanism for the Impairment of Cellular DNA Synthesis

Abstract

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