1887

Abstract

SUMMARY

Prolonged passage of Marek’s disease virus in cell culture resulted in attenuation of the virus and inability of the virus to produce the membrane antigen. However, the apathogenic herpes virus of turkeys produced a serologically similar membrane antigen. Cell culture passage did not cause any change in production of intracellular antigens.

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/content/journal/jgv/10.1099/0022-1317-21-1-193
1973-10-01
2024-04-24
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References

  1. Ahmed M., Schidlovsk G. 1972; Detection of virus associated antigens on membrane of cells productively infected with Marek’s disease virus. Cancer Research 32:187–92
    [Google Scholar]
  2. Calnek B. W., Hitcher S. B. 1969; Localization of viral antigen in chickens infected with Marek’disease herpes-virus. Journal of the National Cancer Institute 43:935–949
    [Google Scholar]
  3. Chen J. H., Purchase H. G. 1970; Surface antigens on chick kidney cells infected with the herpes virus of Marek’s disease. Virology 40:410–412
    [Google Scholar]
  4. Churchill A. E., Bigss P. M. 1967; Agent of Marek’s disease in tissue culture. Nature, London 215:528–530
    [Google Scholar]
  5. Churchill A. E., Chubb R. C., Baxendale W. 1969; The attenuation, with loss of oncogenicity of the herpes virus of Marek’s disease (strain HPRS-16) on passage in cell culture. Journal of General Virology 4:557–564
    [Google Scholar]
  6. Nazerian R. 1970; Attenuation of Marek’s disease virus and study of its properties in two different cell cultures. Journal of the National Cancer Institute 44:1257–1267
    [Google Scholar]
  7. Nazerian K., Purchase H. G. 1970; Combined fluorescent antibody and electron microscopy study of Marek’s disease virus infected cell cultures. Journal of Virologys 5:79
    [Google Scholar]
  8. Nazerian K., Solomon J. J., Witter R. L., Burmester B. R. 1968; Studies on the etiology of Marek’s disease. I. Finding of a herpes virus. Proceedings of the Society for Experimental Biology and Medicine 127:177–183
    [Google Scholar]
  9. Purchase H. G. 1969; Immunofluorescence in the study of Marek’s disease. I. Detection of antigen in cell culture and an antigeriic comparison of eight isolates. Journal of Virology 3:557–569
    [Google Scholar]
  10. Purchase H. G. 1970; Virus specific immunofluorescent and precipitin antigens and cell free virus in tissues of birds infected with Marek’s disease virus. Cancer Research 30:1898–1908
    [Google Scholar]
  11. Rodriguez J., Deinhardt F. 1960; Preparation of semi-permanent mounting medium for fluorescent-antibody studies. Virology 12:316–320
    [Google Scholar]
  12. Witter R. L., Nazerian K., Purchase H. G., Burgoyne H. H. 1970; Isolation from turkeys of a cell-associated herpes virus antigenically related to Marek’s disease virus. American Journal of Veterinary Research 31:525–53
    [Google Scholar]
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