Long Term Infection of Diploid African Green Monkey Brain Cells by Schwarz Measles Vaccine Virus Free

Abstract

SUMMARY

A long-term infection of African green monkey brain (AGMBr) cells with Schwarz measles vaccine virus was established and maintained for 13 infected cell passages over 482 days. Results indicated that the majority of these cells contained latent, non-infectious virus and offered a useful tissue culture model for the study of measles virus in brain tissue. AGMBr cells infected with Edmonston ‘wild’ or SSPE-1 (an isolate from a patient with subacute sclerosing panencephalitis) could not be maintained beyond 2 passages.

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1973-09-01
2024-03-29
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