1887

Abstract

Summary

The relationship of group-specific (hexon) antigen, type-specific (fibre) antigen, soluble haemagglutinin (dodecon) and purified virus particles of adenovirus 19 was studied by cross complement-fixation, haemagglutination- inhibition and neutralization with antisera prepared against purified antigens.

The fibre antigen reacted as an indirect haemagglutinin, producing haemag- glutination in the presence of selected heterologous adenovirus immune sera. Dodecon and fibre antigen were closely related, while hexon antigen showed no relationship to fibre and possibly a weak relationship to dodecon antigen. Neutralizing antibodies were found in antisera to hexon and dodecon, but not in fibre antisera.

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/content/journal/jgv/10.1099/0022-1317-2-3-331
1968-05-01
2022-01-16
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