@article{mbs:/content/journal/jgv/10.1099/0022-1317-17-3-281, author = "Barlow, D. F.", title = "The Effects of Various Protecting Agents on the Inactivation of Foot-and-Mouth Disease Virus in Aerosols and during Freeze-drying", journal= "Journal of General Virology", year = "1972", volume = "17", number = "3", pages = "281-288", doi = "https://doi.org/10.1099/0022-1317-17-3-281", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-17-3-281", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "SUMMARY Inositol, sodium glutamate and calcium lactobionate were found to protect foot-and-mouth disease virus against inactivation during spraying and equilibration in the first 1s in aerosols. They also protected virus against inactivation during freeze-drying. Dimethyl sulphoxide and glycerol both protected virus against the inactivation which occurred between 1s and 5 min in aerosols, but they did not protect during freeze-drying. Pre-humidification before sampling reduced the inactivation of virus, particularly at 40% r.h. The different protective mechanisms of these compounds and of pre-humidification are discussed in relation to the mechanisms of aerosol inactivation.", }