1887

Abstract

SUMMARY

The DNA’s of the simian adenoviruses studied belong to three groups that can be distinguished on the basis of DNA-DNA hybridization techniques: one nononcogenic group and two groups of oncogenic viruses. However, DNA base composition studies reveal at most a bimodal distribution of values, and the mol. wt. of these DNA’s is randomly distributed between 17 and 23 million.

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1972-12-01
2024-04-19
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References

  1. Burnett J. P., Harrington J. A. 1968; Simian adenovirus SA7: chemical, physical, and biological properties. Proceedings of the National Academy of Sciences of the United States of America 60:1023–1029
    [Google Scholar]
  2. Burnett J. P., , Summers A. O., , Harrington J. A., Dwyer A. C. 1968; Production of highly labelled adenovirus. Applied Microbiology 16:1245–1250
    [Google Scholar]
  3. Cowie D. B., , Avery R. J., Champe S. P. 1971; DNA homology among the T-even bacteriophages. Virology 45:30–37
    [Google Scholar]
  4. Denhardt D. T. 1966; A membrane-filter technique for the detection of complementary DNA. Biochemical and Biophysical Research Communications 23:641–646
    [Google Scholar]
  5. Freeman A. E., Black P. H., Vanderpool E. A., Henry P. H., Austin J. B., Huebner R. J. 1967; Transformation of primary rat embryo cells by adenovirus type 2. Proceedings of the National Academy of Sciences of the United States of America 58:1205–1211
    [Google Scholar]
  6. Gilden R. V., Kern J., Heberling R. L., Huebner R. J. 1968; Serological studies of the T and tumor antigens of the oncogenic simian adenoviruses. Applied Microbiology 16:1015–1018
    [Google Scholar]
  7. Goodheart C. R. 1971; DNA density of oncogenic and non-oncogenic simian adenoviruses. Virology 44:645–648
    [Google Scholar]
  8. Hull R. N. 1968 The simian viruses. In Virology Monographs vol. 11 p. 1–66 New York: Springer-Verlag;
    [Google Scholar]
  9. Hull R. N., Johnson I. S., Culbertson C. B., Wright H. W. 1965; Oncogenicity of the simian adenoviruses. Science, New York 150:1044–1046
    [Google Scholar]
  10. Mccarthy B. J., Mcconaughy B. L. 1968; Related base sequences in the DNA of simple and complex organisms. I. DNA/DNA duplex formation and the incidence of partially related base sequences inDNA. Biochemical Genetics 2:37–53
    [Google Scholar]
  11. Malherbe H., Harwin R. 1963; The cytopathic effects of vervet monkey viruses. South African Medical Journal 37:407–411
    [Google Scholar]
  12. Mandel M., Marmur J. 1968 Use of ultraviolet absorbance-temperature profile for determining the guanine plus cytosine content of DNA. In Methods in Enzymology vol. xii p. 195–206 New York & London: Academic Press;
    [Google Scholar]
  13. Mayne N., Burnett J. P., Butler L. K. 1971; Tumour induction by simian adenovirus SA7 DNA fragments. Nature New Biology 232:182–183
    [Google Scholar]
  14. Pina M., Green M. 1965; Biochemical studies on adenovirus multiplication. IX. Chemical and base composition analysis of 28 human adenoviruses. Proceedings of the National Academy of Sciences of the United States of America 54:547–551
    [Google Scholar]
  15. Piña M., Green M. 1968; Base composition of the DNA of oncogenic simian adenovirus SA7 and homology with human adenovirus DNA’s. Virology 36:321–323
    [Google Scholar]
  16. Quétier F., Guillé E., Lejus L. 1969; Equilibrium density gradient ultracentrifugation: a simple computer program for routine DNA analysis. Archives of Biochemistry and Biophysics 130:685–687
    [Google Scholar]
  17. Rapoza N. P., Cheever F. S. 1966; Classification and identification of simian adenoviruses by haemag-glutination, hemagglutination-inhibition techniques. Federation Proceedings 25:340
    [Google Scholar]
  18. Schildkraut C. L., Marmur J., Doty P. 1962; Determination of the base composition of deoxyribonucleic acid from its buoyant density in CsCl. Journal of Molecular Biology 4:430–443
    [Google Scholar]
  19. Schlesinger R. W. 1969 Adenoviruses: the nature of the virion and of the controlling factors in productive or abortive infection and tumorigenesis. In Advances in Virus Research vol. xiv p. 1–61 New York & London: Academic Press;
    [Google Scholar]
  20. Slifkin J., Merkow L., Rapoza N. P. 1968; Tumor induction by simian adenovirus 30 and establishment of tumour cell lines. Cancer Research 28:1173–1179
    [Google Scholar]
  21. Studier F. W. 1965; Sedimentation studies of the size and shape of DNA. Journal of Molecular Biology 11:373–390
    [Google Scholar]
  22. Szybalski W. 1968 Use of cesium sulfate for equilibrium density gradient centrifugation. In Methods in Enzymology vol. xii pp. 330–360 New York & London: Academic Press;
    [Google Scholar]
  23. Vinograd J., Bruner R., Kent R., Weigle J. 1963; Band-centrifugation of macromolecules and viruses in self-generating density gradients. Proceedings of the National Academy of Sciences of the United States ofAmerica 49:902–910
    [Google Scholar]
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