%0 Journal Article %A Cartwright, B. %A Brown, F. %T Serological Relationships between Different Strains of Vesicular Stomatis Virus %D 1972 %J Journal of General Virology, %V 16 %N 3 %P 391-398 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-16-3-391 %I Microbiology Society, %X SUMMARY The five vesicular stomatitis viruses Indiana, New Jersey, Cocal, Argentina and Brazil have been examined for cross-relationships by complement fixing and neutralization tests. With the exception of the Cocal and Argentina strains, intact virus particles showed little cross-reaction in either test. However, the infective skeleton-like structure produced by uncoating the virus with Tween-ether or Nonidet, and the infective ribonucleoprotein (RNP) produced by deoxycholate disruption of the virus, were neutralized by either homo- or heterotypic antisera and showed considerable cross-reactivity in the complement fixation test. Experiments with the isolated sub-units of the virus indicated that the major part of the cross-reactivity was associated with the RNP. The morphologically similar Piry and Chandipura viruses appeared to be unrelated to the vesicular stomatitis group in both complement fixation and neutralization tests. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-16-3-391