1887

Abstract

Summary

The five vesicular stomatitis viruses Indiana, New Jersey, Cocal, Argentina and Brazil have been examined for cross-relationships by complement fixing and neutralization tests. With the exception of the Cocal and Argentina strains, intact virus particles showed little cross-reaction in either test. However, the infective skeleton-like structure produced by uncoating the virus with Tween-ether or Nonidet, and the infective ribonucleoprotein (RNP) produced by deoxycholate disruption of the virus, were neutralized by either homo- or heterotypic antisera and showed considerable cross-reactivity in the complement fixation test. Experiments with the isolated sub-units of the virus indicated that the major part of the cross-reactivity was associated with the RNP. The morphologically similar Piry and Chandipura viruses appeared to be unrelated to the vesicular stomatitis group in both complement fixation and neutralization tests.

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/content/journal/jgv/10.1099/0022-1317-16-3-391
1972-09-01
2019-10-19
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-16-3-391
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