1887

Abstract

SUMMARY

Significant virus autointerference was not observed in serial undiluted passages of vesicular stomatitis virus in Madin–Darby canine kidney cells. The ultra-structural features of vesicular stomatitis virus development into Madin–Darby canine kidney cells were studied by staining frozen-thawed cells with ferritin-conjugated antibody. The granular and fibrillar antigen could be readily identified in the cytoplasm within 4 hr after infection. Its appearance was followed closely by the differentiation of virus filaments at the cell surface. The virus antigen could be recognized in close proximity to virus particles; this material may represent virus nucleoprotein incorporated into budding virus particles.

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/content/journal/jgv/10.1099/0022-1317-13-1-27
1971-10-01
2022-01-17
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