1887

Abstract

SUMMARY

During serial passage of mouse embryo fibroblasts it was found that an established line of cells was more susceptible to murine sarcoma virus transformation than early passages of the cells from which it was derived. An explanation can be made in terms of the growth rates of the cells involved, although primary cells were more susceptible to murine sarcoma virus than would be expected from their rate of growth. Non-dividing (amitotic) cells were not susceptible to murine sarcoma virus transformation.

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1971-08-01
2022-06-29
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References

  1. Aaronson S. A., Todaro G. J. 1968; Development of 3T3-like lines from Balb/c mouse embryo cultures: transformation susceptibility to SV40. Journal of Cell Physiology 72:141
    [Google Scholar]
  2. Baltimore D. 1970; Viral RNA-dependent DNA polymerase. Nature, London 226:1209
    [Google Scholar]
  3. Bather R., Leonard A., Yang J. 1968; Characteristics of the in vitro assay of murine sarcoma virus (moloney) and virus-infected cells. Journal of the National Cancer Institute 40:551
    [Google Scholar]
  4. Buck B. M., Bather T. 1969; Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (moloney). Journal of General Virology 4:457
    [Google Scholar]
  5. Coggin J. H. 1969; Enhanced virus transformation of hamster embryo cells in vitro . Journal of Virology 3:458
    [Google Scholar]
  6. Eagle H. 1965; Growth regulating effects of cellular interactions. Israel Journal of Medical Science 1:1220
    [Google Scholar]
  7. Gude W. D., Upton A. C., Odell T. T. 1955; Giemsa staining of autoradiograms prepared with stripping film. Stain Technology 30:161
    [Google Scholar]
  8. Hartley J. W., Rowe W. P. 1966; Production of altered cell foci in tissue culture by defective moloney sarcoma virus particles. Proceedings of the National Academy of Sciences of the United States of America 55:780
    [Google Scholar]
  9. Harvey J. J. 1968; Replication of murine sarcoma virus-HARVEY in tissue cultures of virus-induced sarcomas. Journal of General Virology 3:327
    [Google Scholar]
  10. Hirschman S. Z., Fischinger P. J., Zaccari J. J., O’connor J. R. 1969; Effect of cytosine arabinoside on the replication of the Moloney sarcoma virus in 3T3 cell cultures. Journal of the National Cancer Institute 42:399
    [Google Scholar]
  11. Jainchill J. L., Aaronson S. A., Todaro G. J. 1969; Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibiting mouse cells. Journal of Virology 4:549
    [Google Scholar]
  12. Levinthal J. D., Rubin H. 1968; Serum induced changes in the fine structure of primary chick embryo cultures. Experimental Cell Research 52:667
    [Google Scholar]
  13. Murray R. K., Temin H. M. 1970; Carcinogenesis by RNA sarcoma viruses. XIV. Infection of stationary cultures with murine sarcoma virus (harvey). International Journal of Cancer 5:320
    [Google Scholar]
  14. Nakata Y., Bader J. P. 1968; Transformation by murine sarcoma virus: fixation (deoxyribonucleic acid synthesis) and development. Journal of Virology 2:1255
    [Google Scholar]
  15. Sarma P. S., Cheong M. P., Hartley J. W., Huebner R. J. 1967; A viral interference test for mouse leukemia viruses. Virology 33:180
    [Google Scholar]
  16. Simons P. J. 1970; The behaviour of two strains of murine sarcoma virus in vitro . Australian Journal of Experimental Biology and Medical Science 48:105
    [Google Scholar]
  17. Simons P. J., Dourmashkin R. R., Turano A., Phillips D. E. H., Chesterman F. C. 1967; Morphological transformation of mouse embryo cells in vitro by murine sarcoma virus (harvey). Nature, London 214:897
    [Google Scholar]
  18. Simons P. J., Mccully D. J. 1970; Pathologic and virologic studies of tumors induced in mice by two strains of murine sarcoma vims. Journal of the National Cancer Institute 44:1289
    [Google Scholar]
  19. Simons P. J., Pepper S. S., Baker R. S. U. 1969; Different cell culture characteristics of two strains of murine sarcoma virus. Proceedings of the Society for Experimental Biology and Medicine, New York 131:454
    [Google Scholar]
  20. Stanley N. F., Dorman D. C., Ponsford J. 1953; Studies on the pathogenesis of a hitherto undescribed virus (Hepato-encephalomyelitis) producing unusual symptoms in suckling mice. Australian Journal of Experimental Biology and Medical Sciences 31:147
    [Google Scholar]
  21. Swim H. E. 1959; Microbiological aspects of tissue culture. Annual Review of Microbiology 13:141
    [Google Scholar]
  22. Temin H. M., Mizutani S. 1970; RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature, London 226:1211
    [Google Scholar]
  23. Tjio J. H., Puck T. T. 1958; Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in tissue culture. Journal of Experimental Medicine 108:259
    [Google Scholar]
  24. Todaro G. J., Green H. 1963; Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. Journal of Cell Biology 17:299
    [Google Scholar]
  25. Todaro G. J., Wolman S. R., Green H. 1963; Rapid transformation of human fibroblasts with low growth potential into established lines by SV 40. Journal of Cellular and Comparative Physiology 62:257
    [Google Scholar]
  26. Yoshikura H. 1970a; Dependence of murine sarcoma virus infection on the cell cycle. Journal of General Virology 6:183
    [Google Scholar]
  27. Yoshikura H. 1970b; Radiological studies on the chronological relation between murine sarcoma virus infection and cell cycle. Journal of General Virology 8:113
    [Google Scholar]
  28. Yoshikura H., Hirokawa Y., Ikawa Y., Sugano H. 1968; Transformation of a mouse cell line by murine sarcoma virus (moloney). International Journal of Cancer 3:743
    [Google Scholar]
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