1887

Abstract

SUMMARY

Bovine syncytial virus was found to replicate in BHK 21 cells. A thin-section study of the morphogenesis of the virus in BHK 21 cells indicated that virus precursor is formed in the nucleus and, in some cells at least, is liberated into the cytoplasm by breakdown of the nuclear envelope. Internal components were found in the nucleus and the cytoplasm and also embedded in the chromosomes of dividing nuclei. Virus internal components gained their envelopes by budding through one of a variety of cytoplasmic membranes, including the plasma membrane. Some stages of the morphogenesis of bovine syncytial virus in BESp cells, and of a type 1 simian foamy virus in BHK 21 cells, are also illustrated. It is concluded that bovine syncytial virus, a feline agent and simian foamy agents all belong to the same virus group.

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/content/journal/jgv/10.1099/0022-1317-12-2-105
1971-08-01
2022-09-25
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References

  1. Anonymous Communication 1966; Suggestions for the classification of oncogenic RNA viruses. Journal of the National Cancer Institute 37:395
    [Google Scholar]
  2. Boothe A. D., Van Der Maaten M. J., Malmquist W. A. 1970; Morphological variation of a syncytial virus from lymphosarcomatous and apparently normal cattle. Archiv für die gesamte Virusforschung 31:373
    [Google Scholar]
  3. Clarke J. K., Attridge J. T. 1968; The morphology of simian foamy agents. Journal of General Virology 3:185
    [Google Scholar]
  4. Clarke J. K., Attridge J. T., Gay F. W. 1969a; The morphogenesis of simian foamy agents. Journal of General Virology 4:183
    [Google Scholar]
  5. Clarke J. K., Gay F. W., Attridge J. T. 1969b; Replication of simian foamy virus in monkey kidney cells. Journal of Virology 3:358
    [Google Scholar]
  6. Clarke J. K., McFerran J. B. 1970; The morphology of bovine syncytial virus. Journal of General Virology 9155
    [Google Scholar]
  7. Gard S., Rockborn G. 1963; Tissue culture studies of bovine leukosis. Proceedings of the 17th World Veterinary Congress, Hannover 1555 Hannover: Hahn-Druckerei;
    [Google Scholar]
  8. Hsuing G. D. 1969; The major groups of simian viruses. In Infections and immunosuppression in subhuman primates Ed. by Balner H., Beveridge W. I. B. Munksgaard: Scandinavian University Books;
    [Google Scholar]
  9. Jordan L. E., Plummer G., Mayor H. D. 1965; The fine structure of foamy virus. Virology 25:156
    [Google Scholar]
  10. Malmquist W. A., Van Der Maaten M. J., Boothe A. D. 1969; Isolation, immunodiffusion, immunofluorescence and electron microscopy of a syncytial virus of lymphosarcomatous and apparently normal cattle. Cancer Research 29:188
    [Google Scholar]
  11. McKissick G. E., Lamont P. H. 1970; Characteristics of a virus isolated from a feline fibrosarcoma. Journal of Virology 5:247
    [Google Scholar]
  12. Riggs J. L., Oshiro L. S., Taylor D. O. N., Lennette E. H. 1969; Syncytium-forming agent isolated from domestic cats. Nature, London 222:1190
    [Google Scholar]
  13. Sjolund R. D., Shik C. Y. 1970; Virus particles in nuclei of cultured plant cells which have lost the ability to differentiate. Proceedings of the National Academy of Sciences of the United States of America 66:25
    [Google Scholar]
  14. Thomas J.A., Delain E., Hollande E. 1967; Morphogénèse d’un virus du Hamster associé à la souche BHK ou à des tumeurs. Comptes rendus hebdomadaires des séances de IʼAcadémie des Sciences 264:785
    [Google Scholar]
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