1887

Abstract

Summary

Infection of primary human embryo kidney cells with adenovirus types 2, 7, 12, 18 and 31, at a multiplicity of infection of 2, resulted in the induction of chromosome aberrations in metaphases examined 24 hr after infection. The aberrations induced by types 2 and 7 were randomly distributed over the karyotype, but types 12 and 31, and to a lesser extent type 18, all induced non-random effects. Both type 12 and type 31 produced chromatid and isochromatid gaps and breaks at a specific site on chromosome no. 17.

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/content/journal/jgv/10.1099/0022-1317-12-1-43
1971-07-01
2019-10-21
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-12-1-43
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