The Inhibition of Polyoma Antigen Synthesis and Capsid Formation by 5-fluorodeoxyuridine

P. Urbano

doi:10.1099/0022-1317-1-3-291

The Inhibition of Polyoma Antigen Synthesis and Capsid Formation by 5-fluorodeoxyuridine

P. Urbano
First Published: 01 July 1967 https://doi.org/10.1099/0022-1317-1-3-291

Abstract

Summary

In mouse embryo cells infected with polyoma virus, inhibition of DNA replication by fluorodeoxyuridine (10 µm) suppressed the production of haemagglutinin, infectious virus and viral antigen as judged by direct immunofluorescence. No virus-like particles were detected in extracts of inhibited cultures examined by electron microscopy.

Received: 14/12/1966
Accepted: 24/02/1967
Published Online: 01/07/1967

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Journal of General Virology

Volume 1, Issue 3

Research Article

Free

The Inhibition of Polyoma Antigen Synthesis and Capsid Formation by 5-fluorodeoxyuridine

Abstract

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