1887

Abstract

Six clinical isolates of a hitherto unknown, strictly anaerobic, Gram-negative rod showing fastidious growth were subjected to a polyphasic taxonomic study, including phenotypic, genomic and phylogenetic feature analyses. 16S rRNA gene sequenced-based phylogeny revealed that the novel strains represent a homogeneous group distant from any recognized species in the candidate phylum ‘’. The novel isolates were most closely related to species of the genus , with 88.2–88.7 % 16S rRNA gene sequence similarity. Large-scale chromosome structure and DNA G+C content also differentiated the novel strains from members of the genus . The novel strains were asaccharolytic. Major metabolic end products in trypticase/glucose/yeast extract broth were acetic, lactic, succinic and isovaleric acids and the major cellular fatty acids iso-C and C. Based on the data presented here, a new genus, gen. nov., is proposed with one novel species, sp. nov. is the first characterized species of the candidate phylum ‘’ that includes human isolates. The G+C content of the DNA of the type strain of ADV 126 (=AIP 136.05=CIP 109408=CCUG 53819) is 59.4 mol%.

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2007-12-01
2019-10-22
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