%0 Journal Article %A Falsen, Enevold %A Collins, Matthew D. %A Welinder-Olsson, Christina %A Song, Yuli %A Finegold, Sydney M. %A Lawson, Paul A. %T Fastidiosipila sanguinis gen. nov., sp. nov., a new Gram-positive, coccus-shaped organism from human blood %D 2005 %J International Journal of Systematic and Evolutionary Microbiology, %V 55 %N 2 %P 853-858 %@ 1466-5034 %R https://doi.org/10.1099/ijs.0.63327-0 %I Microbiology Society, %X Phenotypic and phylogenetic studies were performed on two strains of an unidentified Gram-positive, fastidious, non-spore-forming, coccus-shaped bacterium recovered from human blood. The organism was catalase-negative and grew under strictly anaerobic conditions and in the presence of 2 and 6 % O2. Comparative 16S rRNA gene sequencing demonstrated that the unidentified bacterium was, phylogenetically, far removed from peptostreptococci and related Gram-positive coccus-shaped organisms, but exhibited a phylogenetic association with Clostridium rRNA cluster III [as defined by Collins et al., Int J Syst Bacteriol 44 (1994), 812–826 ]. Sequence divergence values of 15 % or more were observed between the unidentified bacterium and all other recognized species within this and related rRNA clostridial clusters. Treeing analysis showed that the unknown bacterium formed a deep line branching at the periphery of rRNA cluster III and represents a hitherto unknown genus within this supra-generic grouping. On the basis of both phylogenetic and phenotypic evidence, it is proposed that the unknown bacterium from blood be classified in a new genus, Fastidiosipila gen. nov., as Fastidiosipila sanguinis sp. nov. The type strain of Fastidiosipila sanguinis is CCUG 47711T (=CIP 108292T). %U https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijs.0.63327-0