1887

Abstract

Since the original description of sp. nov. in 2009, additional samples available from humans and ticks from Europe and Mongolia, respectively, have been used to further characterize strains belonging to this group of spirochaetes that utilize rodents as reservoir hosts. These investigations suggested the presence of related strains in Europe and Asia and confirmed their status as representing a distinct species. Furthermore, samples that were investigated by researchers from China and Japan confirm the ecological relationship of members of this proposed species with rodents and suggest that it has a wide distribution in Eurasia. Here, we use phylogenetic and genetic distance analyses to validate sp. nov. as a species within the species complex. The type strain is PBi ( = DSM 23469 = BAA-2496).

Funding
This study was supported by the:
  • Bavarian Ministry for Environment and Health (StMUG)
  • Robert Koch-Institut
Loading

Article metrics loading...

/content/journal/ijsem/10.1099/ijs.0.052001-0
2013-11-01
2021-07-26
Loading full text...

Full text loading...

/deliver/fulltext/ijsem/63/11/4284.html?itemId=/content/journal/ijsem/10.1099/ijs.0.052001-0&mimeType=html&fmt=ahah

References

  1. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. ( 1992 ). Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. . Int J Syst Bacteriol 42, 378383. [View Article] [PubMed]
    [Google Scholar]
  2. Bishop C. J., Aanensen D. M., Jordan G. E., Kilian M., Hanage W. P., Spratt B. G. ( 2009 ). Assigning strains to bacterial species via the internet. . BMC Biol 7, 3. [View Article] [PubMed]
    [Google Scholar]
  3. Dubska L., Literak I., Kocianova E., Taragelova V., Sychra O. ( 2009 ). Differential role of passerine birds in distribution of Borrelia spirochetes, based on data from ticks collected from birds during the postbreeding migration period in Central Europe. . Appl Environ Microbiol 75, 596602. [View Article] [PubMed]
    [Google Scholar]
  4. Fingerle V., Schulte-Spechtel U. C., Ruzic-Sabljic E., Leonhard S., Hofmann H., Weber K., Pfister K., Strle F., Wilske B. ( 2008 ). Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov.. Int J Med Microbiol 298, 279290. [View Article] [PubMed]
    [Google Scholar]
  5. Fukunaga M., Hamase A., Okada K., Nakao M. ( 1996 ). Borrelia tanukii sp. nov. and Borrelia turdae sp. nov. found from ixodid ticks in Japan: rapid species identification by 16S rRNA gene-targeted PCR analysis. . Microbiol Immunol 40, 877881.[PubMed] [CrossRef]
    [Google Scholar]
  6. Gevers D., Cohan F. M., Lawrence J. G., Spratt B. G., Coenye T., Feil E. J., Stackebrandt E., Van de Peer Y., Vandamme P. & other authors ( 2005 ). Opinion: Re-evaluating prokaryotic species. . Nat Rev Microbiol 3, 733739. [View Article] [PubMed]
    [Google Scholar]
  7. Hanincová K., Taragelová V., Koci J., Schäfer S. M., Hails R., Ullmann A. J., Piesman J., Labuda M., Kurtenbach K. ( 2003b ). Association of Borrelia garinii and B. valaisiana with songbirds in Slovakia. . Appl Environ Microbiol 69, 28252830. [View Article] [PubMed]
    [Google Scholar]
  8. Hu C. M., Humair P. F., Wallich R., Gern L. ( 1997 ). Apodemus sp. rodents, reservoir hosts for Borrelia afzelii in an endemic area in Switzerland. . Zentralbl Bakteriol 285, 558564. [View Article] [PubMed]
    [Google Scholar]
  9. Hu C. M., Wilske B., Fingerle V., Lobet Y., Gern L. ( 2001 ). Transmission of Borrelia garinii OspA serotype 4 to BALB/c mice by Ixodes ricinus ticks collected in the field. . J Clin Microbiol 39, 11691171. [View Article] [PubMed]
    [Google Scholar]
  10. Huegli D., Hu C. M., Humair P. F., Wilske B., Gern L. ( 2002 ). Apodemus species mice are reservoir hosts of Borrelia garinii OspA serotype 4 in Switzerland. . J Clin Microbiol 40, 47354737. [View Article] [PubMed]
    [Google Scholar]
  11. Johnson R. C., Schmid G. P., Hyde F. W., Steigerwalt A. G., Brenner D. J. ( 1984 ). Borrelia burgdorferi sp. nov.: etiological agent of Lyme disease. . Int J Syst Bacteriol 34, 496497. [View Article]
    [Google Scholar]
  12. Koeppel A., Perry E. B., Sikorski J., Krizanc D., Warner A., Ward D. M., Rooney A. P., Brambilla E., Connor N. & other authors ( 2008 ). Identifying the fundamental units of bacterial diversity: a paradigm shift to incorporate ecology into bacterial systematics. . Proc Natl Acad Sci U S A 105, 25042509. [View Article] [PubMed]
    [Google Scholar]
  13. Korenberg E. I., Gorelova N. B., Kovalevskii Y. V. ( 2002 ). Ecology of Borrelia burgdorferi sensu lato in Russia. . In Lyme Borreliosis: Biology, Epidemiology and Control. Edited by Gray J., Kahl O., Lane R. S., Stanek G. . Wallingford:: CABI Publishing;. Chaper 7, pp 175200. [View Article]
    [Google Scholar]
  14. Kurtenbach K., Hanincová K., Tsao J. I., Margos G., Fish D., Ogden N. H. ( 2006 ). Fundamental processes in the evolutionary ecology of Lyme borreliosis. . Nat Rev Microbiol 4, 660669. [View Article] [PubMed]
    [Google Scholar]
  15. Le Fleche A., Postic D., Girardet K., Peter O., Baranton G. ( 1997 ). Characterization of Borrelia lusitaniae sp. nov. by 16S ribosomal DNA sequence analysis. . Int J Syst Bacteriol 47, 921925. [View Article] [PubMed]
    [Google Scholar]
  16. Marconi R. T., Hohenberger S., Jauris-Heipke S., Schulte-Spechtel U., LaVoie C. P., Rössler D., Wilske B. ( 1999 ). Genetic analysis of Borrelia garinii OspA serotype 4 strains associated with neuroborreliosis: evidence for extensive genetic homogeneity. . J Clin Microbiol 37, 39653970.[PubMed]
    [Google Scholar]
  17. Margos G., Gatewood A. G., Aanensen D. M., Hanincová K., Terekhova D., Vollmer S. A., Cornet M., Piesman J., Donaghy M. & other authors ( 2008 ). MLST of housekeeping genes captures geographic population structure and suggests a European origin of Borrelia burgdorferi . . Proc Natl Acad Sci U S A 105, 87308735. [View Article] [PubMed]
    [Google Scholar]
  18. Margos G., Vollmer S. A., Cornet M., Garnier M., Fingerle V., Wilske B., Bormane A., Vitorino L., Collares-Pereira M. & other authors ( 2009 ). A new Borrelia species defined by multilocus sequence analysis of housekeeping genes. . Appl Environ Microbiol 75, 54105416. [View Article] [PubMed]
    [Google Scholar]
  19. Masuzawa T., Takada N., Kudeken M., Fukui T., Yano Y., Ishiguro F., Kawamura Y., Imai Y., Ezaki T. ( 2001 ). Borrelia sinica sp. nov., a lyme disease-related Borrelia species isolated in China. . Int J Syst Evol Microbiol 51, 18171824. [View Article] [PubMed]
    [Google Scholar]
  20. Miyamoto K., Masuzawa T. ( 2002 ). Ecology of Borrelia burgdorferi sensu lato in Japan and East Asia. . In Lyme Borreliosis: Biology, Epidemiology and Control, pp. 201222. Edited by Gray J., Kahl O., Lane R. S., Stanek G. . Wallingford:: CABI Publishing;. [View Article]
    [Google Scholar]
  21. Piesman J., Gern L. ( 2004 ). Lyme borreliosis in Europe and North America. . Parasitology 129 (Suppl), S191S220. [View Article] [PubMed]
    [Google Scholar]
  22. Postic D., Belfaiza J., Isogai E., Saint Girons I., Grimont P. A., Baranton G. ( 1993 ). A new genomic species in Borrelia burgdorferi sensu lato isolated from Japanese ticks. . Res Microbiol 144, 467473. [View Article] [PubMed]
    [Google Scholar]
  23. Postic D., Ras N. M., Lane R. S., Hendson M., Baranton G. ( 1998 ). Expanded diversity among Californian borrelia isolates and description of Borrelia bissettii sp. nov. (formerly Borrelia group DN127). . J Clin Microbiol 36, 34973504.[PubMed]
    [Google Scholar]
  24. Postic D., Garnier M., Baranton G. ( 2007 ). Multilocus sequence analysis of atypical Borrelia burgdorferi sensu lato isolates–description of Borrelia californiensis sp. nov., and genomospecies 1 and 2. . Int J Med Microbiol 297, 263271. [View Article] [PubMed]
    [Google Scholar]
  25. Richter D., Postic D., Sertour N., Livey I., Matuschka F. R., Baranton G. ( 2006 ). Delineation of Borrelia burgdorferi sensu lato species by multilocus sequence analysis and confirmation of the delineation of Borrelia spielmanii sp. nov.. Int J Syst Evol Microbiol 56, 873881. [View Article] [PubMed]
    [Google Scholar]
  26. Rudenko N., Golovchenko M., Grubhoffer L., Oliver J. H. Jr ( 2011 ). Borrelia carolinensis sp. nov., a novel species of the Borrelia burgdorferi sensu lato complex isolated from rodents and a tick from the south-eastern USA. . Int J Syst Evol Microbiol 61, 381383. [View Article] [PubMed]
    [Google Scholar]
  27. Scholz H. C., Margos G., Derschum H., Speck S., Tserennorov D., Erdenebat N., Undraa B., Enkhtuja M., Battsetseg J. & other authors ( 2013 ). High prevalence of genetically diverse Borrelia bavariensis-like strains in Ixodes persulcatus from Selenge Aimag, Mongolia. . Ticks Tick Borne Dis 4, 8992. [View Article] [PubMed]
    [Google Scholar]
  28. Takano A., Nakao M., Masuzawa T., Takada N., Yano Y., Ishiguro F., Fujita H., Ito T., Ma X. & other authors ( 2011 ). Multilocus sequence typing implicates rodents as the main reservoir host of human-pathogenic Borrelia garinii in Japan. . J Clin Microbiol 49, 20352039. [View Article] [PubMed]
    [Google Scholar]
  29. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. ( 2011 ). mega5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. . Mol Biol Evol 28, 27312739. [View Article] [PubMed]
    [Google Scholar]
  30. Taragel’ová V., Koci J., Hanincová K., Kurtenbach K., Derdáková M., Ogden N. H., Literák I., Kocianová E., Labuda M. ( 2008 ). Blackbirds and song thrushes constitute a key reservoir of Borrelia garinii, the causative agent of borreliosis in Central Europe. . Appl Environ Microbiol 74, 12891293. [View Article] [PubMed]
    [Google Scholar]
  31. Vollmer S. A., Bormane A., Dinnis R. E., Seelig F., Dobson A. D., Aanensen D. M., James M. C., Donaghy M., Randolph S.E., Feil E. J., Kurtenbach K., Margos G. ( 2011 ). Host migration impacts on the phylogeography of Lyme Borreliosis spirochaete species in Europe. . Environ Microbiol 13, 184192. [View Article] [PubMed]
    [Google Scholar]
  32. Vollmer S. A., Feil E. J., Chu C. Y., Raper S. L., Cao W. C., Kurtenbach K., Margos G. ( 2013 ). Spatial spread and demographic expansion of Lyme borreliosis spirochaetes in Eurasia. . Infect Genet Evol 14, 147155. [View Article] [PubMed]
    [Google Scholar]
  33. Wilske B., Preac-Mursic V., Göbel U. B., Graf B., Jauris S., Soutschek E., Schwab E., Zumstein G. ( 1993 ). An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis. . J Clin Microbiol 31, 340350.[PubMed]
    [Google Scholar]
  34. Wilske B., Busch U., Eiffert H., Fingerle V., Pfister H. W., Rössler D., Preac-Mursic V. ( 1996 ). Diversity of OspA and OspC among cerebrospinal fluid isolates of Borrelia burgdorferi sensu lato from patients with neuroborreliosis in Germany. . Med Microbiol Immunol (Berl) 184, 195201. [View Article] [PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/ijsem/10.1099/ijs.0.052001-0
Loading
/content/journal/ijsem/10.1099/ijs.0.052001-0
Loading

Data & Media loading...

Supplements

Supplementary material 1

PDF

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error