1887

Abstract

A comparison of complex isolates from seals (pinnipeds) in Australia, Argentina, Uruguay, Great Britain and New Zealand was undertaken to determine their relationships to each other and their taxonomic position within the complex. Isolates from 30 cases of tuberculosis in six species of pinniped and seven related isolates were compared to representative and standard strains of the complex. The seal isolates could be distinguished from other members of the complex, including the recently defined ‘’ and ‘’, on the basis of host preference and phenotypic and genetic tests. Pinnipeds appear to be the natural host for this ‘seal bacillus’, although the organism is also pathogenic in guinea pigs, rabbits, humans, Brazilian tapir () and, possibly, cattle. Infection caused by the seal bacillus is predominantly associated with granulomatous lesions in the peripheral lymph nodes, lungs, pleura, spleen and peritoneum. Cases of disseminated disease have been found. As with other members of the complex, aerosols are the most likely route of transmission. The name sp. nov. is proposed for this novel member of the complex (the type strain is 6482=ATCC BAA-688=NCTC 13288).

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2003-09-01
2019-10-21
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