1887

Abstract

A novel strain, 219820, whose metabolites were found to be active against tumour cells, was isolated and characterized. The isolate belonged to the genus and had white to grey aerial mycelium and long chains of smooth spores in the aerial mycelium. A phylogenetic tree based on 16S rRNA gene sequences showed that strain 219820 had highest similarity to members of the genus and was most closely, albeit loosely, associated with NBRC 15401 (98.624 % similarity), NBRC 12890 (98.565 %) and NBRC 13065 (98.564 %). However, DNA–DNA relatedness and phenotypic data readily distinguished strain 219820 from these phylogenetically related type strains. It is evident from the combination of genotypic and phenotypic data that strain 219820 represents a novel species of the genus , for which the name sp. nov. is proposed; the type strain is 219820 ( = CGMCC 4.5626  = DSM 42014).

Funding
This study was supported by the:
  • National High Technology Research and Development Program of China (Award 2007AA09Z415)
  • National Natural Science Foundation of China (Award U0633008)
  • National Nonprofit Institute Research Grant (Award ITBBZD0753)
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2011-07-01
2024-04-20
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