RT Journal Article SR Electronic(1) A1 Kitahara, M A1 Takamine, F A1 Imamura, T A1 Benno, YYR 2001 T1 Clostridium hiranonis sp. nov., a human intestinal bacterium with bile acid 7alpha-dehydroxylating activity. JF International Journal of Systematic and Evolutionary Microbiology, VO 51 IS 1 SP 39 OP 44 DO https://doi.org/10.1099/00207713-51-1-39 PB Microbiology Society, SN 1466-5034, AB The Clostridium-like organisms TO-931T and HD-17, isolated from human faeces, have high levels of bile acid 7alpha-dehydroxylating activity. Sequencing of their 16S rDNA demonstrated that they belong to cluster XI of the genus Clostridium and that they represent a new and distinct line of descent. Clostridium bifermentans and Clostridium sordellii in cluster XI also possess bile acid 7alpha-dehydroxylating activity. DNA-DNA hybridization experiments with the isolates, TO-931T and HD-17, and C bifermentans and C. sordellii revealed that the isolates are a single species distinct from C. bifermentans and C sordellii. On the basis of phylogenetic analysis, using 16S rDNA sequences, and DNA-DNA hybridization analysis, it is concluded that strains TO-931T and HD-17 are members of a new species of the genus Clostridium, for which the name Clostridium hiranonis is proposed. The type strain is strain TO-931T (= JCM 10541T = DSM 13275T)., UL https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/00207713-51-1-39