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Deoxyribonucleic acid of Mycobacterium lepraemurium grown in mice was isolated and analyzed spectrophotometrically. The genome molecular weight and guanine-plus-cytosine content of this M. lepraemurium deoxyribonucleic acid were 1.8 × 109 and 65.5 mol%, respectively. Among selected strains of mycobacterial species, four strains of Mycobacterium avium showed the highest degree of deoxyribonucleic acid homology (74.2 to 92.9%) with M. lepraemurium, suggesting a close genetic relatedness.
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