@article{mbs:/content/journal/ijsem/10.1099/00207713-32-4-419, author = "REDDY, C. A. and CORNELL, C. P. and FRAGA, A. M.", title = "Transfer of Corynebacterium pyogenes (Glage) Eberson to the Genus Actinomyces as Actinomyces pyogenes (Glage) comb. nov†", journal= "International Journal of Systematic and Evolutionary Microbiology", year = "1982", volume = "32", number = "4", pages = "419-429", doi = "https://doi.org/10.1099/00207713-32-4-419", url = "https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/00207713-32-4-419", publisher = "Microbiology Society", issn = "1466-5034", type = "Journal Article", abstract = "The physiology, metabolism, nutrition, and biochemical characteristics of Corynebacterium pyogenes (Glage) Eberson were studied in detail to determine the taxonomic status of this organism. C. pyogenes is a gram-positive, nonmotile, nonsporulating, short, rod-shaped bacterium which produces acid but not gas from a variety of carbohydrates. A number of amino acids were tested and did not appear to serve as sources of energy for growth. C. pyogenes is urease and catalase negative, does not reduce nitrates, and does not produce indole. Wide zones of β-hemolysis on blood agar, acid coagulation of litmus milk, and digestion of the clot are characteristic. Growth is comparable under aerobic and strictly anaerobic conditions. Metabolism is strictly fermentative. Glucose is fermented in CO2-containing media to succinate, acetate, formate, and lactate; no propionic acid is produced. In identical media without CO2, lactate is the major product, and only small amounts of acetate, succinate, and formate are produced. Hemin is stimulatory or required for growth. CO2/HCO3 – and inositol seem to be obligatory growth factors. Certain peptides appear to relieve the requirement for inositol. All strains require riboflavin and nicotinic acid, and most require adenine and uracil for optimal growth. Characteristic cell wall sugar components are rhamnose and glucose, and the major diamino acid of peptidoglycan is lysine. Cells contain a type b cytochrome. Based on these data, we propose that C. pyogenes be transferred to the genus Actinomyces as Actinomyces pyogenes (Glage) comb. nov.", }