Heterogeneity of Thymidine Kinase Among Species of and Free

Abstract

The thymidine kinase activities present in nine strains (including four type strains and one neotype strain) of nine species of the genus and two strains (including one type strain) of two species of the genus were characterized with respect to migration in polyacrylamide gels and isoelectric point as determined by electrofocusing. There was a marked heterogeneity in the enzymes, not only between the two genera but also within each genus.

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1980-01-01
2024-03-28
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References

  1. Bacchetti S., Graham F. L. 1977; Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cell by purified herpes simplex viral DNA. Proc. Natl. Acad. Sci. U.S.A 74:1590–1594
    [Google Scholar]
  2. McGee Z. A., Rogul M., Wittier R. G. 1967; Molecular genetic studies of relationships among mycoplasma, L-forms and bacteria. Ann. N.Y. Acad. Sci 143:21–30
    [Google Scholar]
  3. Munyon W., Buchsbaum R., Paoletti E., Mann J., Kraiaelburd E., Davis D. 1972; Electrophoresis of thymidine kinase activity synthesized by cells transformed by herpes simplex virus. Virology 49:683–689
    [Google Scholar]
  4. Munyon W., Kraiselburd E., Davis D., Mann J. 1971; Transfer of thymidine kinase to thymidine kinaseless L cells by infection with ultraviolet-irradiated herpes simplex virus. J. Virol 7:813–820
    [Google Scholar]
  5. Reich P. R., Somerson N. L., Hybner C. J., Chanock R. M., Weissman S. M. 1966; Genetic differentiation of nucleic acid homology. J. Bacteriol 92:302–310
    [Google Scholar]
  6. Reich P. R., Somerson N. L., Rose J. A., Weissman S. M. 1966; Genetic relatedness among mycoplasmas as determined by nucleic acid homology. J. Bacteriol 91:153–160
    [Google Scholar]
  7. Russell W. C. 1966; Alterations in the nucleic acid me tabolism of tissue culture cells infected by mycoplasmas. Nature (London) 212:1537–1540
    [Google Scholar]
  8. Stanbridge E. J., Tischfield J. A., Schneider E. L. 1975; Appearance of hypoxanthine guanine phosphoribosyl transferase activity as a consequence of mycoplasma contamination. Nature (London) 256:329–331
    [Google Scholar]
  9. Stock D. A., Gentry G. A. 1971; Thymidine me tabolism in Mycoplasma hominis. . J. Gen. Microbiol 65:105–107
    [Google Scholar]
  10. Van Diggelen O. P., McGarrity G. J., Shin S.-I. 1978; Endogenous HPRT activity in mycoplasmas isolated from cell cultures. In Vitro 14:734–739
    [Google Scholar]
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