Deoxyribonucleic acids (DNA) were extracted from strains of and and were compared by DNA-DNA hybridization. When their DNAs were compared by hybridization on membrane filters, from humans were barely separable from strains, but strains from hamsters were distinctly different. strains from veterinary infections were identical to human strains. With the use of the more sensitive S nuclease hybridization method with DNA from a set of strains that had been used in a numerical taxonomy study, typical strains from humans could be distinguished from typical strains. A group of atypical strains could also be delineated. The results generally parallel the taxonomic divisions of these organisms based on serology or numerical taxonomy. strains from humans and strains are similar but distinguishable, but strains from hamsters are clearly separable.


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