RT Journal Article SR Electronic(1) A1 COYKENDALL, ALAN L. A1 MUNZENMAIER, ALLAN J.YR 1978 T1 Deoxyribonucleic Acid Base Sequence Studies on Glucan-Producing and Glucan-Negative Strains of Streptococcus mitior JF International Journal of Systematic and Evolutionary Microbiology, VO 28 IS 4 SP 511 OP 515 DO https://doi.org/10.1099/00207713-28-4-511 PB Microbiology Society, SN 1466-5034, AB The deoxyribonucleic acid base sequence similarities among 14 strains of Streptococcus mitior were assessed by hybridization. Some strains produce glucan. Deoxyribonucleic acid was purified by both a conventional method and by centrifugation in CsCl. Hybridizations were done in solution with S1 nuclease and on membrane filters. The results showed two groups of moderately homologous strains. The glucan-producing strains represented a group which included some glucan-negative strains. Hybridization by the S1 method was less than with the filter method, indicating some sequence divergence within the two groups. There was a slight difference in guanine-plus-cytosine contents of the two groups., UL https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/00207713-28-4-511