1887

Abstract

Forty strains of (Schroeter) Migula isolated from clinical specimens and producing a water-soluble brown pigment on peptone media were compared with the neotype and nine other non-brown strains of The brown pigment is formed from either tyrosine or phenylalanine through the accumulation of homogentisic acid and has no identity with DOPA melanin. A new term, “pyomelanin,” is proposed for this brown pigment synthesized by certain strains of Although the pyomelanin strains share the attributes of the species, some of them have a more limited capacity with regard to certain biochemical reactions than the neotype strain of A careful examination is required to identify these aberrant strains. Actively growing cells of pyomelanin strains converted tyrosine to pyomelanin, but tyrosine itself does not appear to serve as a sole source of carbon and nitrogen for growth. A simple method of differentiating pyomelanin-producing strains of from pyorubin-producing strains is presented. To recognize properly the species, the attributes of pyomelanin strains should be included in descriptions of

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1972-04-01
2024-04-19
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