Trans-cinnamaldehyde - geraniol mixture – antibacterial activity and haemotoxicity

The aim of this study was to test the antibacterial activity and haemotoxicity of (trans)-cinnamaldehyde and geraniol. Conducted analyzes showed that (trans)-cinnamaldehyde-geraniol mixture have antibacterial properties against S. aureus ATCC6538, E. coli ATCC8739 and P. aeruginosa KKP991. MIC and MBC of the mixture was determined for each strain. For S. aureus MIC=0.065 mg/ml, MBC=1.25 mg/ml, for E. coli MIC= 0.5 mg/ml, MBC=1 mg/ml and for P. aeruginosa MIC=0.5 mg/ml, MBC=1.25 mg/ml. Also the blood compatibility test was done, and it showed that MIC for S. aureus (0.025 mg/ml) is non-haemotoxic, but other MICs and all MBCs, unfortunately are.