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Abstract

This was a cross sectional and observational study, conducted in the Department of Microbiology, Sylhet MAG Osmani Medical College, Sylhet. The study period was from July 2010 to June 2011 in objective to explore the Varicella-Zoster virus immune status (VZV-IgG) in pregnant mothers and neonates up to six months post birth. For this purpose, 60 pregnant women, 60 new born babies and 60 infants aged six months were selected. The mean age of the pregnant woman was 28.8 (SD±4.7) years. The sex of new born babies and six months aged infants was identical [29 (48.3 %) male vs 31 (51.7 %) male; P=0.715]. Seroprevalence rate of IgG antibody of Varicella-Zoster Virus in Pregnant, mothers 81.7%, in new born babies 78.3 % and in infants aged six months were 10.0 %. The seropositivity of VZV IgG level in both pregnant mothers and newborn babies were almost similar but the infant aged six months were significantly lower than that of new born babies (p This showed that a significant proportion of Bangladeshi pregnant mother is susceptible to varicella and infant aged six months is highly susceptible to varicella. Any vaccination strategy must have to take into account these epidemiological variability of the country.

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/content/journal/acmi/10.1099/acmi.ac2019.po0038
2019-04-08
2020-01-29
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http://instance.metastore.ingenta.com/content/journal/acmi/10.1099/acmi.ac2019.po0038
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