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Abstract

Tuberculosis (TB) remains one of the world’s leading causes of morbidity and mortality. It occurs in both pulmonary and extra-pulmonary forms. Primary iliac bone TB remains a rare clinical entity, even in endemic areas. The diagnosis of the disease can be challenging due to its similarity to other bone diseases. We report a rare case of primary iliac bone TB in a 63-year-old patient who was on peritoneal dialysis and had a medical history of hypertension and type II diabetes, which was complicated by diabetic retinopathy and diabetic kidney disease. Magnetic resonance imaging revealed osteomyelitis in the iliac bone, while real-time polymerase chain reaction using the GeneXpert system on a gluteal collection sample confirmed the diagnosis of TB. The integration of advanced molecular tools, such as GeneXpert, represents significant progress, enabling rapid and accurate diagnosis of TB and facilitating early initiation of treatment.

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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/content/journal/acmi/10.1099/acmi.0.000844.v3
2025-05-07
2025-05-13
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References

  1. Yadav S. Primary isoniazid mono-resistant pulmonary tuberculosis in a COVID-19-positive male: world's first case of its kind in the present pandemic. Cureus 2022; 14:e27163 [View Article] [PubMed]
    [Google Scholar]
  2. Ministry of Health and Social Protection National strategic plan for the prevention and control of tuberculosis in Morocco 2024–2030; 2023 https://www.sante.gov.ma/Documents/2023/11/strat%C3%A9gie%20DH%202024-2030.pdf
  3. World Health Organization Global tuberculosis report; 2024 https://iris.who.int/bitstream/handle/10665/379339/9789240101531-eng.pdf
  4. Jain M, Sarkar S, Naik S, Behera S. Iliac bone tuberculosis with bicompartmental abscess. BMJ Case Rep 2018; 2018:bcr2018226606 [View Article] [PubMed]
    [Google Scholar]
  5. Stingo FE, Rodriguez-Fontan F, Burger-Van der Walt E, Arce J, Garcia SN et al. Isolated iliac crest tuberculosis: a case report. JBJS Case Connect 2018; 8:e31 [View Article] [PubMed]
    [Google Scholar]
  6. Romanowski K, Clark EG, Levin A, Cook VJ, Johnston JC. Tuberculosis and chronic kidney disease: an emerging global syndemic. Kidney Int 2016; 90:34–40 [View Article] [PubMed]
    [Google Scholar]
  7. Al-Efraij K, Mota L, Lunny C, Schachter M, Cook V et al. Risk of active tuberculosis in chronic kidney disease: a systematic review and meta-analysis. Int J Tuberc Lung Dis 2015; 19:1493–1499 [View Article] [PubMed]
    [Google Scholar]
  8. El Amrani M, Asserraji M, Bahadi A, El Kabbaj D, Benyahia M. Tuberculosis in hemodialysis. la tuberculose en hémodialyse. Med Sante Trop 2016; 26:262–266 [View Article]
    [Google Scholar]
  9. Chen L, Zhou W, Hu P, Zhou Z. A series of tuberculous cold abscesses at uncommon anatomic sites. Quant Imaging Med Surg 2023; 13:5393–5397 [View Article] [PubMed]
    [Google Scholar]
  10. Norbis L, Alagna R, Tortoli E, Codecasa LR, Migliori GB et al. Challenges and perspectives in the diagnosis of extrapulmonary tuberculosis. Expert Rev Anti Infect Ther 2014; 12:633–647 [View Article] [PubMed]
    [Google Scholar]
  11. Sharma SK, Mohan A, Kohli M. Extrapulmonary tuberculosis. Expert Rev Respir Med 2021; 15:931–948 [View Article] [PubMed]
    [Google Scholar]
  12. Jabri H, Lakhdar N, El Khattabi W, Afif H. Diagnostic means for tuberculosis. Rev Pneumol Clin 2016; 72:320–325 [View Article] [PubMed]
    [Google Scholar]
  13. Minion J, Pai M, Ramsay A, Menzies D, Greenaway C. Comparison of LED and conventional fluorescence microscopy for detection of acid fast bacilli in a low-incidence setting. PLoS One 2011; 6:e22495 [View Article] [PubMed]
    [Google Scholar]
  14. World Health Organization Global tuberculosis report; 2014 p 237 http://apps.who.int/iris/bitstream/10665/137094/1/9789241564809
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