Skip to content
1887

Abstract

Disseminated gonococcal infections (DGIs) are a rare but often debilitating complication of infections. Often presenting as arthritis–dermatitis syndrome, true suppurative joint infections are an even more rare form of DGI. Here, we present the first known case of DGI in Newfoundland and Labrador in over 10 years.

A 50-year-old man who is known to inject drugs with multiple housing and social challenges presented to the emergency department with a 2-day history of an isolated, painful, erythematous knee. After being assessed by orthopaedics and undergoing an operative debridement, intraoperative cultures grew . He was treated with intravenous ceftriaxone, and his course in hospital was complicated by inadequate pain control and a lack of stable housing.

Although rare, DGIs need to remain on every clinician’s differential for septic arthritis, given the increasing prevalence of gonorrhoeal infections in Canada, particularly in Newfoundland and Labrador. In addition, patients who are at risk of delaying accessing care, such as people who inject drugs and unhoused individuals, are at higher risk of complicated hospital stays.

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
Loading

Article metrics loading...

/content/journal/acmi/10.1099/acmi.0.000807.v3
2025-01-30
2026-04-15

Metrics

Loading full text...

Full text loading...

/deliver/fulltext/acmi/7/1/acmi000807.v3.html?itemId=/content/journal/acmi/10.1099/acmi.0.000807.v3&mimeType=html&fmt=ahah

References

  1. Kirkcaldy RD, Weston E, Segurado AC, Hughes G. Epidemiology of gonorrhoea: a global perspective. Sex Health 2019; 16:401–411 [View Article] [PubMed]
    [Google Scholar]
  2. Public Health Agency of Canada Report on sexually transmitted infection surveillance in canada, 2019; 2022 https://www.canada.ca/en/public-health/services/publications/diseases-conditions/report-sexually-transmitted-infection-surveillance-canada-2019.html accessed 17 November 2023
  3. Newfoundland Labrador Canada Surveillance and disease reports - health and community services; 2020 https://www.gov.nl.ca/hcs/publichealth/cdc/informationandsurveillance/ accessed 17 November 2023
  4. Weston EJ, Heidenga BL, Farley MM, Tunali A, D’Angelo MT et al. Surveillance for disseminated gonococcal infections, Active Bacterial Core Surveillance (ABCs)-United States, 2015-2019. Clin Infect Dis 2022; 75:953–958 [View Article] [PubMed]
    [Google Scholar]
  5. Birrell JM, Gunathilake M, Singleton S, Williams S, Krause V. Characteristics and impact of disseminated gonococcal infection in the “Top End” of Australia. Am J Trop Med Hyg 2019; 101:753–760 [View Article] [PubMed]
    [Google Scholar]
  6. Public Health Agency of Canada Enhanced surveillance of antimicrobial-resistant gonorrhea in canada (infographic); 2022 https://www.canada.ca/en/public-health/services/publications/diseases-conditions/enhanced-surveillance-antimicrobial-resistant-gonorrhea-canada-infographic.html accessed 17 November 2023
  7. Bardin T. Gonococcal arthritis. Best Pract Res Clin Rheumatol 2003; 17:201–208 [View Article] [PubMed]
    [Google Scholar]
  8. O’Brien JP, Goldenberg DL, Rice PA. Disseminated gonococcal infection: a prospective analysis of 49 patients and a review of pathophysiology and immune mechanisms. Medicine 1983; 62:395–406 [PubMed]
    [Google Scholar]
  9. Wang DA, Tambyah PA. Septic arthritis in immunocompetent and immunosuppressed hosts. Best Pract Res Clin Rheumatol 2015; 29:275–289 [View Article] [PubMed]
    [Google Scholar]
  10. Tan DHS, Hull MW, Yoong D, Tremblay C, O’Byrne P et al. Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis. CMAJ 2017; 189:E1448–E1458 [View Article]
    [Google Scholar]
  11. Handsfield HH, Lipman TO, Harnisch JP, Tronca E, Holmes KK. Asymptomatic gonorrhea in men. Diagnosis, natural course, prevalence and significance. N Engl J Med 1974; 290:117–123 [View Article] [PubMed]
    [Google Scholar]
  12. McCormack WM, Johnson K, Stumacher R, Donner A, Rychwalski R. Clinical spectrum of gonococcal infection in women. Lancet 1977; 309:1182–1185 [View Article]
    [Google Scholar]
  13. Sawatzky P, Martin I, Thorington R, Alexander D. Disseminated gonococcal infections in Manitoba, Canada: 2013 to 2020. Sex Transm Dis 2022; 49:831–837 [View Article] [PubMed]
    [Google Scholar]
  14. CATIE Doxycycline to help prevent bacterial STIs; 2024 https://www.catie.ca/doxycycline
  15. Garpenhag L, Dahlman D. Perceived healthcare stigma among patients in opioid substitution treatment: a qualitative study. Subst Abuse Treat Prev Policy 2021; 16:81 [View Article] [PubMed]
    [Google Scholar]
  16. Cheetham A, Picco L, Barnett A, Lubman DI, Nielsen S. The impact of stigma on people with opioid use disorder, opioid treatment, and policy. Subst Abuse Rehabil 2022; 13:1–12 [View Article] [PubMed]
    [Google Scholar]
  17. Gilmer C, Buccieri K. Homeless patients associate clinician bias with suboptimal care for mental illness, addictions, and chronic pain. J Prim Care Community Health 2020; 11:2150132720910289 [View Article] [PubMed]
    [Google Scholar]
  18. Li R, Hatcher JD. Gonococcal arthritis Treasure Island (FL): StatPearls Publishing; 2023 https://www.ncbi.nlm.nih.gov/books/NBK470439/ accessed 29 May 2023
    [Google Scholar]
  19. Rice PA. Gonococcal arthritis (disseminated gonococcal infection). Infect Dis Clin North Am 2005; 19:853–861 [View Article] [PubMed]
    [Google Scholar]
  20. Talley J. The impact of social stigmas on sexual health seeking behavior: a review of literature. McNair Sch Res J 2020; 13:
    [Google Scholar]
  21. Baxter AJ, Tweed EJ, Katikireddi SV, Thomson H. Effects of housing first approaches on health and well-being of adults who are homeless or at risk of homelessness: systematic review and meta-analysis of randomised controlled trials. J Epidemiol Community Health 2019; 73:379–387 [View Article] [PubMed]
    [Google Scholar]
/content/journal/acmi/10.1099/acmi.0.000807.v3
Loading
/content/journal/acmi/10.1099/acmi.0.000807.v3
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An error occurred
Approval was partially successful, following selected items could not be processed due to error