1887

Abstract

The Group A Streptococcus (GAS), also known as (), is a human pathogen causing various infections, ranging from mild, such as tonsillitis and impetigo, to severe and invasive conditions like septicemia and necrotizing fasciitis. Despite a decline in incidence and severity during the twentieth century due to antibiotics, there has been a reported increase in severe cases since the 1980s in industrialized countries. is a human pathogen with a natural reservoir in the pharynx and skin, exhibits asymptomatic carriage in various body sites. It is responsible for a spectrum of clinical manifestations, from asymptomatic carriage to severe invasive infections. Transmission occurs through respiratory droplets or direct contact with skin lesions. Bacteriologically, is a Gram-positive β-hemolytic streptococcus. This summary highlights a case of invasive Group A Streptococcus infection in a 28-year-old diagnosed at the microbiology laboratory of the Mohammed V Military Training Hospital in Rabat, Morocco. A 28-year-old patient, without any specific medical history, presented with acute febrile oligoarthritis. Following a recent flu-like syndrome and febrile tonsillitis, the patient experienced asymmetric inflammatory oligoarthralgia affecting the left knee, left ankle, and right shoulder, accompanied by functional impairment of the left lower limb. Upon admission, clinical examination revealed swelling, positive patellar tap, and sternal involvement. Laboratory and imaging findings indicated an abscessed collection in the left knee and anterior mediastinitis. Emergency aspirations revealed Group A Streptococcus, specifically , leading to a diagnosis of septic arthritis. Dual antibiotic therapy and knee joint drainage resulted in symptom resolution after 45 days. The rise in severe Group A Streptococcus infection underscores the need for early detection and treatment. Widely sharing the French High Council for Public Health’s antibiotic prophylaxis recommendations is crucial for awareness. Collaborating between clinicians and microbiologists is essential for effective management.

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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/content/journal/acmi/10.1099/acmi.0.000767.v3
2024-07-08
2024-07-13
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References

  1. Martin JM. Pharyngitis and streptococcal throat infections. Pediatr Ann 2010; 39:22–27 [View Article] [PubMed]
    [Google Scholar]
  2. Caillet-Gossot S, Rousset-Rouviere C, Arlaud K, Dubus J-C, Bosdure E. Clustered cases of intrafamily invasive Streptococcus pyogenes infection (or group A streptococcus). Arch Pediatr 2011; 18:1305–1309 [View Article] [PubMed]
    [Google Scholar]
  3. Mhamdi G. Pyogenic septic arthritis: clinical and Microbiological profile; 2020 https://doi.org/10.1016/j.medmal.2020.06.255
  4. Veyssier-Belot C, Lèvy-Bruhl D, Carret G, Bouvet A, Portier H. Infections invasives à Streptococcus pyogenes. Médecine et Maladies Infectieuses 2004; 34S14–S16 [View Article]
    [Google Scholar]
  5. Denis F, Christian Martin M-C, Cattoir V. Bactériologie médicale, techniques usuelles. In 28.3 Famille Des Streptococcaceae et Des Enterococcaceae, 3rd edn. 2016 p 272
    [Google Scholar]
  6. EUCAST European society of clinical microbiology and infections diseases. In Comité de l’antibiogramme de La Société Française de Microbiologie Recommandations 2023
    [Google Scholar]
  7. Yu D, Gao W, Guo D, Lu Q, Chen Y et al. Case report: septic arthritis in children caused by Streptococcus pyogenes-rational use of antibiotics. Front Cell Infect Microbiol 2023; 12:1117217 [View Article] [PubMed]
    [Google Scholar]
  8. CSHPF Opinion of the higher council of public health of France on the conduct to be taken around one or more cases of community origin of invasive infections with Streptococcus pyogenes (or group A Streptococci); 2005 http://www.hcsp.fr accessed 18 November 2005
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