Skip to content
1887

Abstract

, belonging to the order , is a rare and emerging human pathogen reported to cause both superficial and invasive infections. The 13 case reports in the literature worldwide highlight blood, bone and wound infections. To our knowledge this is the first case description of causing a urinary tract infection in a 69-year-old immunocompetent patient which was isolated in two separate specimens and identified using matrix-assisted laser desorption ionization time-of-flight MS. It was found to be susceptible to most antimicrobials but resistant to penicillin, amoxicillin-clavulanate, cefoxitin and colistin. Inducible chromosomal resistance was demonstrated on disc approximation testing, and YOC-1 class C beta-lactamase, beta lactamase superfamily and MBL fold metallo-hydrolase genes were found on whole genome sequencing.

Keyword(s): AmpC , UTI and Yokenella
Funding
This study was supported by the:
  • Christian Medical College, Vellore (Award Funded by the institutional Fluid research grant. Institutional review board (IRB) [IRB Min No. 14847 dated 28.09.2022])
    • Principal Award Recipient: RaniDiana Sahni
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Loading

Article metrics loading...

/content/journal/acmi/10.1099/acmi.0.000571.v4
2023-10-16
2026-03-08

Metrics

Loading full text...

Full text loading...

/deliver/fulltext/acmi/5/10/acmi000571.v4.html?itemId=/content/journal/acmi/10.1099/acmi.0.000571.v4&mimeType=html&fmt=ahah

References

  1. Lee SM, Kang YJ, Huh HJ, Ki CS, Lee NY. First report of Yokenella regensburgei isolated from the wound exudate after disarticulation due to diabetic foot infection in Korea. Ann Clin Microbiol 2015; 18:135 [View Article]
    [Google Scholar]
  2. Wright WF, Utz JL, Bruckhart C, Baghli S, Janda JM. Yokenella regensburgei necrotizing fasciitis in an immunocompromised host. J Infect Chemother 2019; 25:816–819 [View Article] [PubMed]
    [Google Scholar]
  3. Aziz ZS. Emerging of Yokenella regensburgei as Uropathogen: first report. J Biol 2015; 6:
    [Google Scholar]
  4. CLSI Performance Standards for Antimicrobial Susceptibility Testing. In CLSI Supplement M100, 32nd. edn Clinical and Laboratory Standards Institute; 2022
    [Google Scholar]
  5. Pérez-Pérez FJ, Hanson ND. Detection of plasmid-mediated AmpC beta-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol 2002; 40:2153–2162 [View Article] [PubMed]
    [Google Scholar]
  6. Lo Y-C, Chuang Y-W, Lin Y-H. Yokenella regensburgei in an immunocompromised host: a case report and review of the literature. Infection 2011; 39:485–488 [View Article] [PubMed]
    [Google Scholar]
  7. Stock I, Sherwood KJ, Wiedemann B. Antimicrobial susceptibility patterns, beta-lactamases, and biochemical identification of Yokenella regensburgei strains. Diagn Microbiol Infect Dis 2004; 48:5–15 [View Article] [PubMed]
    [Google Scholar]
  8. Karen C. C, Michael A. P, Marie Louise L, Robin P, McAdam AJ. Manual of Clinical Microbiology ASM PR; 2019
    [Google Scholar]
/content/journal/acmi/10.1099/acmi.0.000571.v4
Loading
/content/journal/acmi/10.1099/acmi.0.000571.v4
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An error occurred
Approval was partially successful, following selected items could not be processed due to error