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Volume 4, Issue 3

Successful treatment of vancomycin-resistant enterococcal infection of an external ventricular drain with 2 weeks of intravenous linezolid Open Access

Abstract

Hydrocephalus is a common condition worldwide, and is frequently managed by diversion of cerebrospinal fluid (CSF), either externally with a drain or internally with a shunt. An external ventricular drain (EVD) can be an essential treatment modality, but is associated with a risk of infection, most commonly caused by species, which can result in meningitis or ventriculitis and a delay in the definitive management of the hydrocephalus. Here, we report the case of a patient who required an EVD to manage post-operative hydrocephalus following a craniotomy and microvascular decompression for trigeminal neuralgia. He subsequently developed EVD-associated infection with a vancomycin-resistant (VRE), which was treated successfully with a 2-week course of intravenous linezolid monotherapy. The authors believe this to be the only described case of successful treatment within this time frame of a CSF VRE infection associated with indwelling foreign material.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): external ventricular drain , hydrocephalus , linezolid and vancomycin-resistant enterococcus
© 2022 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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/content/journal/acmi/10.1099/acmi.0.000335
2022-03-29
2025-01-24
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/content/journal/acmi/10.1099/acmi.0.000335
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Successful treatment of vancomycin-resistant enterococcal infection of an external ventricular drain with 2 weeks of intravenous linezolid
Access Microbiology 4, 000335 (2022); https://doi.org/10.1099/acmi.0.000335
/content/journal/acmi/10.1099/acmi.0.000335
/content/journal/acmi/10.1099/acmi.0.000335
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